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Fasten your Belt

Health is becoming more of a common topic with the vast majority of people being more involved and interested in promoting thief own health and well-being.

So many dietary regimes have been practiced and many have quickly risen and similarly faded away.

Few have remained, and lesser are now gaining popularity to almost becoming the lifestyle for many.

I’m going to talk about two types

Intermittent fasting

Intermittent fasting is one of the most popular programs being adopted by people all over the world.

There are several forms of intermittent fasting (IF). The principle is adopting fasting periods beyond the duration of an overnight fast and restricting feeding time windows, with or without caloric restriction.

A few examples are below:

Time-restricted feeding/eating (TRF), eating is limited to a certain number of hours each day.

Alternate-day fasting (ADF) as the name applies, consists of alternating days of feasting and fasting —feasting is compatible with liberal energy intake during 24 h and fasting implicates a restricted caloric intake ≤ 25% of daily needs ( less than 600 kcal during 24 h)

intermittent energy restriction (IER): It includes periods of energy restriction alternated with periods of habitual intake or minimally restricted dietary intake, allowing wider food choices. This approach helps “cheating” our metabolic rate to avoid going into starvation mode and keep burning calories.

continuous energy restriction (CER) for improving body composition. This has the potential of steering our metabolism to a slow energy-conserving mode. Thus, after an initial satisfactory weight loss, it becomes challenging to shed off more weight. Hence, this method is better avoided.

The ultimate goal of most IF regimens is to improve body composition. For this reason, they are suggested to maximize the loss of fat mass (FM), while attempting to preserve fat-free mass (FFM).

There is compelling evidence that IF elicits reductions in body weight and FM of ~3–8%, Improvements in blood lipid profile, blood pressure and insulin sensitivity.

Whist IF has recently emerged and increasingly gained popularity, its possible predecessor has been around for about 1400 years.

Ramadan fasting

During the 9th month (Ramadan) of the Islamic calendar (Hijra) many millions of adult Muslims all over the world fast during the daylight hours. Since Hijri calendar is 11 days shorter, Ramadan occurs at different times in the seasonal year over a 33-year cycle.

During Ramadan, Muslims abstain from ingesting food and liquids between sunrise and sunset throughout a month-long period. Thus, food and liquid intake become exclusively nocturnal.

Ramadan fasting (RF) can last ~12–18 h/day, depending on the geographic location and season of the year. Reductions in body weight, relative FM, and resting metabolic rate are common consequences of RF. It has also been shown that RF decreases total cholesterol, low-density lipoprotein (LDL), and fasting blood glucose levels. In parallel, RF seems to improve body composition, possibly through enhancements in the ability to mobilize saturated fatty acids for metabolic processes.

In the general population, weight loss subsequent to RF is largely caused by the unconscious restriction of food intake.

In addition, there is a metabolic shift toward the predominant use of fatty acids as fuel for adenosine triphosphate (ATP) synthesis during RF and this lowers body fat.

However, despite representing an important opportunity for some people to lose bodyweight and FM, the adaptations inherent to RF are typically transient and largely reversible within a small amount of time.

Thus, the prescription of maintenance strategies at the termination of Ramadan is of extreme value for the long-term preservation of healthy body composition.

Fluid intake during Ramadan

Water, which makes up around 70% of our bodies, is the most important fluid that replenishes our thirst and energy, especially during the month of Ramadan. Studies have shown that reduced intake of water affects our bodies on a cellular level and causes problems in their proper functioning because dehydration has many adverse side effects such as constipation, headaches, dizziness, tiredness, and dry skin.

During the daylight hours of RF, practicing Muslims are undoubtedly dehydrating, but it is not clear whether they are chronically hypohydrated during the month of Ramadan. No detrimental effects on health have as yet been directly attributed to negative water balance at the levels that may be produced during Ramadan.

Not only is water important for weight loss and maintenance, it also helps to get rid of harmful toxins and reduce the feeling of hunger. Due to these and various other reasons, it is imperative that we keep ourselves properly hydrated throughout the day.


Here are a few pointers to help you out:

Increase water intake
Drink at least eight glasses of water every day. If you are exercising or are outdoors in hot weather, you’ll sweat more and lose more fluids. So, ensure you increase your water intake to make up for this excessive loss.

Avoid salty food
Reduce the amount of salt in your food, as foods containing high volumes of sodium trigger thirst throughout the fasting hours of the day.

Add fruits and vegetables to your meals
Eat fresh fruits and vegetables instead of salty foods because they are rich in water and fiber. They stay in the intestines for long, retaining water and hence suppressing your thirst.

Avoid drinking large quantities in one go
Refrain from drinking large quantities of water all at once or a lot during a meal. Instead, have small sips during the meal and drink water in between your meals between sehr and iftar.

Avoid juices and sugary fluids
Do not drink juices to break your fast as it contains high amounts of sugar leading to weight gain. Instead, try and stick with just water.

Add dates to your Iftar menu
Break the fast with dates. Not only is this a tradition because that’s how the Prophet Muhammad (PBUH) broke his fast; dates also help with hydration since they are a natural source of glucose, which encourages your cells to store fluid and fuel for energy.

Ramadan Mubarak!

References:

Frontiersin

Nature

islamicfinder

Festive Seasons and their Effects on your Urinary System

Christmas has just passed and we are still in the partying mode, preparing for the new year. It’s been tough couple of years with yet another wave, albeit less virulent, of COVID’s new disguise; Omicron.

We are on the verge of winning our war against it. It’s indeed worth the celebration. One has to be careful though with the effects of alcohol on our urinary system. The Celebration should not be at the expense of our health and the safety of people around us. Here are some facts about alcohol and its effects on our urinary system.

The effect of Alcohol on the kidneys:

Alcohol alters the filtration function of the kidneys adversely resulting in the reduction of its efficacy, thus rendering them less able to filter the blood.

Alcohol also affects the ability to regulate fluid and electrolytes in the body. It has a natural diuretic effect leading to frequent visits to the toilet after many drinks. This, however, leads to intracellular dehydration, resulting in loss of excess fluid and an Increase in electrolyte concentration in the body.

Regular heavy drinking has been found to double the risk of chronic kidney disease, which does not go away over time. Even a higher risk of kidney problems has been found for heavy drinkers who also smoke.

The Centers for Disease Control estimates that most American adults (two out of three) drink alcohol. Too often, some of these regular drinkers have more than five drinks at one time. In fact, about a quarter of drinkers reported they had done this on at least one day in the past year. “Binge” drinking is even worse. It has harmful effects on the kidney that can even lead to acute kidney failure. A sudden drop in kidney function is called acute kidney failure. This often goes away after a time, but it can occasionally lead to lasting kidney damage.

Added to that is the effect of chronic drinking on the increase in blood pressure resulting in different levels of kidney damage with protein loss in the urine.

Studies have demonstrated the effects of chronic alcohol intake on the cellular structure of the building brick of the kidney; The nephron. It’s been shown that the basement membrane of various aspects of the nephron develops an increase in its thickness, therefore hindering its ability to perform its filtration and concentration functions properly.

The effects of alcohol on the urinary bladder:

Alcohol has a double adverse effect on the urinary bladder: It has a strong diuretic affect leading to excessive frequency and urgency.

It will also lead to dehydration resulting in more concentrated urine, which causes burning of micturition by the concentrated urine.

It has been shown previously by various experiments when the bladder gets distended, the intravesical pressure increases to a peek after which (especially in situations not permitting paying visits to the toilet) the pressure drops down simply due to the thinning of the bladder muscle. This results and the reduction and pressure necessary to generate in order to empty the urinary bladder (law of Laplas).

Also, chronic alcohol intake leads to nerve damage resulting in “alcoholic cystopathy”. This would potentially lead to the current urinary retention.

In summary:

Drinking can be fun in certain cultures, let’s be honest. Excessive alcohol intake can lead to injury, accidents, serious embarrassment and long-term health problems. Even drinking small amounts of alcohol increases your cancer risk.

There are a few tips for those who would enjoy having a drink with their family and friends.

  • Eat before drinking to minimize the direct effect of alcohol on your body.
  • Drink plenty of water.
  • Don’t mix alcohol with sugary or energy drinks.
  • Avoid salty snacks – they will make you thirsty and likely to drink more.
  • Be in control of the number of drinks you take: Set yourself a drinks limit and stick to it. Avoid drinking in rounds (especially with friends who drink too much). Try to finish your drink before you start another, rather than topping up your glass.
  • Slow down when you drink: To keep safe, slow down your drinking to 1 drink per hour. You can do this by:
  • drinking non-alcoholic drinks as well as alcoholic drinks
  • drinking water to quench your thirst before you start drinking alcohol
  • opting for low-alcohol drinks. sipping rather than gulping

Wish you a Happy New Year

References:

Appearance and Performance-enhancing Drugs(APED)


So you have been working hard in the gym trying to improve your appearance and performance. Things aren’t moving with the aspired speed. There are other ways to achieve your goal at a much shorter time and minimal side effects, correct?

Wrong! Cutting corners always comes at a price. In addition to the bumpy ride and money spent on APED, you will get some results in improving your “appearance” but at the expense on your performance; both physically and mentally.

Normally cutting corners might get you back in track albeit it at a price. When it comes to using/absolute abusing APEDs, the price is higher, and recovery is significantly longer..

What are APEDs?

  • Anabolic-androgenic steroids. These are synthetic substances similar to the male sex hormone testosterone. They promote the growth of skeletal muscle (anabolic effects) and the development of male sexual characteristics (androgenic effects) in both males and females
  • Non-steroidal anabolics: include insulin, insulin-like growth hormone (IGF), and human growth hormone (HGH)—substances that are produced by the human body and are prescribed for legitimate medical uses but also sometimes misused for performance enhancement.

There are several misused APEDs, these include:

Oral Steroids
• Anadrol (oxymetholone)
• Anavar (oxandrolone)
• Dianabol (methandienone )
• Winstrol (stanozolol)
• Restandol (testosterone undecanoate)
Injectable Steroids
• Deca-Durabolin (nandrolone decanoate)
• Durabolin (nandrolone phenpropionate)
• Depo-Testosterone (testosterone cypionate)
• Agovirin (testosterone propionate)
• Retandrol (testosterone phenylpropionate)
• Equipoise (boldenone undecylenate)

Other Mia-used medications
Many who practice using APED’s would be keen to try other medications that accentuate the function in terms of enhancing their body image. Some are thermogenics. These are compounds used to decrease body fat or to promote leanness versus muscle mass in endurance athletes.

Examples:

  • Xanthines: compounds that increase attention and wakefulness and suppress appetite. Examples are caffeine, the asthma drug theophylline, and theobromine—a substance found in chocolate, coffee, and tea.
  • Sympathomimetics: drugs that are similar in structure and action to epinephrine and norepinephrine—natural chemicals in the body that increase heart rate, constrict blood vessels, and raise blood pressure. An example is ephedrine, which is derived from the ephedra plant. Ephedrine/ephedra used to be included in dietary supplements that promoted weight loss, increased energy, and enhanced athletic performance. In 2004, the FDA banned the U.S. sale of dietary supplements containing ephedrine/ephedra due to various possible health risks including cardiovascular and nervous system effects.
  • Thyroid hormones: substances that regulate metabolism by altering the function of the thyroid. Cytomel is an example.

Cycling, stacking, pyramiding, and plateauing:

There are several traditionally used methods to inappropriately use these drugs; cycling involves taking multiple doses of steroids over a specific period of time, stopping for a period (so called “clearance”), and starting again.

Stacking means taking two or more different anabolic steroids, mixing oral and/or injectable types, and sometimes even taking compounds that are designed for veterinary use.

Pyramiding is taking APEDs for 6 to 12 weeks, tapering gradually rather than starting and finishing a cycle abruptly. At the beginning of a cycle, the person starts with low doses of the drugs being stacked and then slowly increases the doses. In the second half of the cycle, the doses are slowly decreased to zero. This is sometimes followed by a second cycle in which the person continues to train but without drugs. Steroid users believe that pyramiding allows the body time to adjust to the high doses, and the drug-free cycle allows the body’s hormonal system time to recuperate.

Plateauing is another medically unjustified hormonal manipulation whereby steroids are staggered, overlapped, or substituted with another type of steroid to avoid developing tolerance.

Side effects:

The use of anabolic steroids is associated with a wide spectrum of side effects, some of which are mild and others are severe or even life-threatening. Some are temporary and others are semi-permanent or permanent.

One review found 19 deaths in published case reports related to anabolic steroid use between 1990 and 2012.

APEDs effects on body:

Cardiovascular System

Inappropriate use of anabolic steroids could affect the cardiovascular system by raising the blood pressure and interfering with the cardiac function leading to heart failure and cardiac events, in addition to the development of the deranged lipid profile and increasing liability to Venus thrombosis and embolism.

Hormonal System

Abnormal use of steroids leads to disturbance in the hormonal function including testicular atrophy decreased quality and quantity of sperm production degrees libido especially after withdrawal symptoms in addition to sexual dysfunction.

Females with anabolic steroids miss-use will potentially have an adverse effect of these APEDs on the hair leading to frontal boldness, in addition to deepening of the voice. With continued administration of steroids, some of these effects become irreversible. It is commonly believed that anabolic steroids will produce irreversible enlargement of the clitoris in females.

Liver damage

Chronic use of APEDs is associated with impaired liver function, hepatic cysts, and in rare cases, malignancy

Musculoskeletal System

Unjustified use of anabolic steroids in adolescence might potentially lead to premature closure of the growth plates for the bones leading to short stature. In addition, excessive use of anabolic steroids needs to change in stiffening, which might lead to a tendon injury.

Skin

Acne, unsightly and uncomfortably oil skin. Yellowish discoloration in advanced cases of liver damage

Behavioral changes

An experienced andrologist would be able to spot APED users from a distance. There’s a clear agitation and aggression in extreme cases. In addition, anabolic steroid abusers would suffer from anxiety lack of sleep and depression.

Although testosterone replacement in cases of deficiency has a proven fact on improving the cognitive function in the construction ability, younger people using anabolic steroids excessively might suffer from cognitive dysfunction Maile lots of attention span and concentration ability.

How to treat an existing case of a PED miss-use:

This is naturally and multidisciplinary team Approach. This includes the following:

  • Endocrine treatment to restore the answer genic function for those with withdrawal symptoms
  • Antidepressants for those who do not respond to Endocrine replacement therapy
  • Psychological assessment and support for those who are suffering from body dysmorphia.

In summary:

Are the use of appearance and performance-enhancing drugs as an increasing phenomenon at an alarming rate with serious potentially permanent consequences affecting young Adolescence and adults. There needs to be white education about their potential side effects and in case of medical needs for these medications this should take place under strict supervision. Those who are interested in enhancing their appearance and performance should concentrate on the physiological increase by Healthy diet and exercise.

Otherwise, cutting corners by unjustified usage of these medications would possibly give short term results and definitely give long-term consequences

Reference: drugabuse